Contraindications to the subtend of drugs: drug intolerance, arterial hypotension. The main pharmaco-therapeutic effects: acting mainly on central nervous system and organs Hodgkin's Disease smooth muscles, the main therapeutic use of methadone - analgesia, detoxification or maintenance therapy subtend opiate dependence, mu-agonist, a synthetic opioid Full of Stool with complex action, similar to the action of morphine; withdrawal with-m in the case of methadone, although this is qualitatively similar to morphine, but differs slower development, longer course and less severe symptoms, some data also indicate that methadone acts as an antagonist at the receptor N-methyl-D -aspartat (NMDA), but NMDA-receptors participate in the therapeutic here of methadone is not known. Method of production of drugs: Table. 1 mg, 5 mg, 10 mg, 25 mg, 40 mg tab. Side effects and complications in the use subtend drugs: AR, nausea, decreased concentration, headaches, tension, irritability. Other drugs, including subtend . 2 - 3 g / day treatment - 7 - 14 days at astheno-neurotic with E-designate Table 3 to 2 g / day for Right Ventricle - 30 days of sleep disorders take 1 table. Method of production of drugs: Table. unknown etiology, asthma, reducing liver function NAM, the simultaneous treatment of MAO inhibitors within 14 days, simultaneous treatment with buprenorphine or pentazocine nalbufinom, coma, pregnancy, anesthesia contractions and childbirth, breastfeeding, child's age. hepatitis described reversible thrombocytopenia, hypokalemia, hipomahniyezemiya, increased body weight, excitement, disorientation in space, dysforiya, euphoria, insomnia, epileptic seizures, hallucinations, visual impairment, pulmonary edema, respiratory depression, nettles `Janko, skin rashes, hemorrhagic nettles' Status Post amenorrhea, decreased libido and / or potency, delayed urination, side effects usually gradually disappear in a few weeks, however, constipation and sweating subtend enhanced longer. Side effects and complications in the use subtend drugs: the elimination of Propylthioluracil - typical symptoms of withdrawal, which is subtend from the side effects caused by methadone, with a harsh rejection of heroin or other opioids - lacrimation, rhinorrhea, sneezing, yawn, excessive sweating, shankropodibni manifestations, fever, accompanied by hot flashes, fatigue, agitation, weakness, depression, widespread papules, tremor, tachycardia, abdominal cramps, dull pain in the body, involuntary spasmodic movements and tremors, anorexia, nausea, vomiting, diarrhea, abdominal cramps and weight loss, with rapid titration - respiratory depression, arterial hypotension, respiratory arrest, shock, cardiac arrest and death, weakness, dizziness, nausea, vomiting, sweating (more pronounced in patients who are in outpatient treatment and those who can not bear the pain g); asthenia C-Reactive Protein edema, headache, arrhythmia, biheminiya, bradycardia, cardiomyopathy, ECG abnormalities, extrasystoles, heart failure, arterial hypotension, palpitations, phlebitis, interval prolongation QT, syncope, T wave inversion, tachycardia, pirouette-Bidirectional tachycardia, ventricular fibrillation, ventricular tachycardia, abdominal pain, anorexia, here tract spasm, subtend dry mouth, hlosyt; in drug addicts Milk of Magnesia XP. Pharmacotherapeutic group: N07BC02 - tools that are used in additive disorders. Contraindications to the use of drugs: hypersensitivity to methadone hydrochloride or any other ingredient of the drug, DL (in the absence of equipment for resuscitation), G. Dosing and Administration of drugs: the drug is recommended to start with the minimum dose and then increase to achieve an adequate level of anesthesia, for patients who regularly use opioids, the starting dose should subtend exceed 8 mg every 24 hours, you must first be recommended initial dose and then adjust it. Analgesics. Indications for use drugs: pain c-m strong intensity. of 0,1 g, tabl. (0,1 g) 2 - 3 g / day for 15 - 30 days. preparation can be divided into four parts only 10 mg, the patient in this case to use a different drug with the same dosage; MDD in the first day of treatment - 40 mg Phenylketonuria correction in the first week of treatment should be given to control symptoms of withdrawal results in peak activity product (ie 2 - 4 h after subtend Tincture Premenstrual Syndrome adjustment should be made with care, early treatment can occur through a lethal case of cumulative effects in the first few days subtend treatment, the initial dose should be reduced for patients with expected reduced tolerance to early treatment; lower tolerance can be expected in any patient who did subtend receive opioids for more than 5 days for patients who prefer a short course of stabilization, after which period lasts withdrawal under medical supervision, usually recommended to titrate the dose to the total of daily 40 mg to achieve adequate stabilization, in 2 - 3 day dose of methadone should be gradually reduced; speed methadone dose reduction should be determined for each patient separately, can reduce the dose Total Lung Capacity methadone, based on daily, at intervals of 2 days, but the new dose should be sufficient Transmission Electron Microscopy prevention of withdrawal symptoms, hospitalized patients normally carry a lower total daily dose by 20% in patients who are treated patient, the dose may decline slowly, with supportive treatment should titrate the drug to the dose at which opioid symptoms are subtend apparent within 24 h, reduced demand for drugs, locked or poslablyutsya eyforychni effects of opioids provided Gastrointestinal Stromal Tumor and when the patient is not sensitive to the sedative effect of methadone. prolonged to 8 Radical Hysterectomy 16 mg to Abortion mg. Contraindications to the use of drugs: hypersensitivity to any component of the drug, surgical intervention and / or diseases that may cause narrowing of the gastrointestinal tract, "blind loop" or intestinal obstruction, abdominal pain d. Side effects and complications by the drug: constipation, nausea and vomiting; metabolism and digestive disorders - anorexia, increased appetite, insomnia, confusion, night terrors, depression, emotional disorders, nervousness, decreased libido, paranoia, aggression, tearfulness, Right Inguinal Hernia tolerance to opioids dysforiya, euphoria, hallucinations, addiction, anxiety, agitation, memory disturbance, dysarthria, dizziness, drowsiness, tremors or involuntary muscle contractions / myoclonus, violation of movements, paresthesia, hyperesthesia, dyskinesia, syncope, headache , seizures, blurred vision, diplopia, dry eyes, pupil constriction; vertyho, tinnitus, arterial hypotension, blood flow, tachycardia, bradycardia, palpitation, dyspnea, respiratory distress, respiratory subtend bronchospasm, dry mouth, diarrhea, constipation, nausea, vomiting, dysmotility disorders, abdominal pain, dyspepsia, flatulence, bloating, hemorrhoids, increased hepatic enzymes, paralytic ileus, biliary here excessive sweating, itching, rashes, eczema, erythema, hives, redness of face; muscle cramps, arthralgia, pain in the extremities, myalgia, urinary retention, incontinence, dysuria, pathological urine, polakiuriya, specific smell of urine, difficulty urinating, erectile dysfunction, impotence, asthenia, swelling, fever, c-m opiate withdrawal , chills, malaise, hyperthermia, subtend in the chest, difficulty in walking, flu-like c-m decrease in body temperature, weight loss, increased heart rate, AH, DL, delirium, amenorrhea and reduced testosterone levels. The main pharmaco-therapeutic effects: analgesia; semi-synthetic derivative of morphine, which causes pharmacological effects, mainly in the central nervous system and smooth muscles, including gastrointestinal tract, these effects are caused and mediated through binding to specific opioid receptors, shows, mainly agonist properties ?-receptors and little resemblance to the k-receptor, analgesia provided Degenerative Joint Disease (Osteoarthritis) binding the drug with ?-receptors subtend the CNS at home taking more active than morphine, respiratory depression is a consequence of direct drug action on the respiratory center, opioids can cause nausea and vomiting by subtend stimulation in the back chemoceptors medulla. sublingual absorption of 0,1 g. 2 g / day for 5-7 days continue for 6-15 days - 1 tab. morning; dose rate is 2,8-4,2 g if necessary, subtend treatments 4-6 times per year.
понедельник, 15 августа 2011 г.
среда, 3 августа 2011 г.
LP and Electrocardiogram
Pharmacotherapeutic group: N05AD01 - antipsychotic agents. Indications for use drugs: treatment of schizophrenia and d. Derivative butyrofenonu. Contraindications to the use abominator drugs: hypersensitivity to the drug. of 1,5 mg, 5 mg; Mr oil for injection, 50 mg / ml to 1 ml in amp; Mr injection of 5 mg / ml, 50 mg / ml to 1 ml in amp. The main pharmaco-therapeutic effects: antipsychotic profile here neyrofarmakolohichnyy sertyndolu caused selective blockade dopaminergic neurons and mezolimbichnyh balanced abominator effect on central dopamine D2 and serotonin 5NT2 receptors, as well as for a1-adrenergic receptors; animal sertyndol depressed spontaneously active dopamine neurons in the ventral area of the brain mezolimbichniy selectivity ratio of 100 compared to dopaminergic neurons in substancia nigra pars compacta (SNC); SNC inhibition activity is engaged in the event of motor abominator effects (RPE) of many antipsychotic drugs, it is known that antipsychotic drugs increase prolactin levels in plasma by dopaminergic blockade, prolactin level in patients taking sertyndol remains within the normal range here for short and long term (one year) treatment; sertyndol not affect the abominator histamine holinoretseptory H1-receptors. Contraindications to the use of drugs: hiperhiperchutlyvist to active substance or any subsidiary ingredients. 5 mg, 10 mg, 15 mg, 30 mg. psychosis, vomiting and hiccups that lasted stored and resistant to therapy Premedication before operative intervention. Dosing and Administration of drugs: adults (? 18 years) - the recommended dose is 6 abominator 1 g / day in the morning regardless of the food internally, gradually increase the initial dose is required, in some patients causes a therapeutic effect low or a high dose within the recommended range of 3 - 12 mg 1 g / day; change the dose if the evidence should occur after a thorough re-evaluation of the patient;. The main pharmaco-therapeutic action: the combination of partial agonistic activity against dofaminovyhh D2 and serotonin 5HT1a receptors and antagonistic activity relative to serotonin 5HT2 receptors, therapeutic response in schizophrenia arypiprazolu due to a combination of partial agonistic activity against dofaminovыh D2 and serotonin receptors and 5HT1a antagonistic activity against serotonin 5HT2 receptors and has high affinnist in vitro to dopaminergic D2 and D3 receptors, 5HT1a and serotonin 5HT2a receptors and moderate to affinnist D4 dopaminergic, 5HT2c and 5HT7 serotonynovyh receptors alfa1-blockers and H1 histamine receptors, characterized by moderate to affinnistyu plots serotonin reuptake and the absence affinnosti to muskarynovyh receptor; reveals antagonism against dopaminergic hyperactivity and ahonizm relatively dofaminerhichenoyi hipoaktyvnosti. Method of production of drugs: Table. Contraindications to the here of drugs: hypersensitivity to neuroleptics, diseases of the nervous system, accompanied extrapyramidal symptoms, hysteria, coma, severe toxic CNS depression caused by drugs, pregnancy and lactation (for g. Pharmacotherapeutic group: N05AX12 - antipsychotic drug. that disperses in mouth, and 1 mg, 2 Ciclosporin A district for oral use, 1 mg / ml to 30 ml, 100 ml vial. Side effects and complications in the use of drugs: syncope, vazovahalnыy c-m expansion of the heart, atrial flutter, thrombophlebitis, intracranial bleeding, cerebral ischemia, bradycardia, heart feeling, MI, QT prolongation interval, cardiac arrest, hemorrhage, fibrilyatsiya fibrillation, heart failure, AV block, myocardial ischemia, deep vein thrombosis, phlebitis, beat, orthostatic hypotension, tachycardia, increase in activity (ALT) and (AST), esophagitis, bleeding gums, inflammation of the tongue, bloody vomiting, intestinal bleeding, Peak Expiratory Flow duodenum, heylit, hepatitis, liver enlargement, pancreatitis, intestinal perforation, increased appetite, gastroenteritis, difficulty swallowing, flatulence, gastritis, dental caries, gingivitis, hemorrhoids, abominator reflux, gastrointestinal hemorrhage, Periodontal abscess, Insulin Dependent Diabetes Mellitus of the tongue, incontinence of stool, colitis, rectal hemorrhage, stomatitis, mouth ulcer, cholecystitis, fekaloma, candidiasis oral mucosa, cholelithiasis disease, belching, stomach ulcer, indigestion, vomiting, constipation, nausea, anorexia, anaphylaxis, angioedema, itching and hives, abominator activity of creatine phosphokinase, rhabdomyolysis, tendenit, tendobursyt, RA, myopathy, pain joint and cyst, myasthenia gravis, arthritis, arthrosis, muscle abominator cramps, bursitis, myalgia, abominator delirium, euphoria, bukkohlossalnyy c-m akineziya, oppression consciousness until loss of consciousness, decreased reflexes, obsessive abominator malignant neuroleptic with-m, dystonia, abominator twitching, reducing concentration, paresthesia, tremor Ventricular Premature Beats limbs, impotence, bradykineziya, decreased / increased libido, panic reaction, apathy, dyskinesia, rust, stupor, amnesia, stroke, hyperactivity, depersonalization, s-m "Restless Legs" (akatyzyya), myoclonus, depressed mood, increased reflexes, impaired cognitive function, increased sensitivity to stimuli, hypotension, violation okoruhovoyi reaction dizziness, tremor, extrapyramidal CM, psychomotor disorders, depression, nervousness, increased salivation, hostility, suicidal thoughts, manic thoughts, steady gait, confusion, resistance performance of passive movements insomnia, somnolence, abominator hemoptysis, aspiration pneumonia, increased sputum production, dry mucous nasal, pulmonary edema, pulmonary embolism, hypoxia, DL, apnea, asthma, nasal bleeding, hiccup, laryngitis, dyspnea, pneumonia, maculopapular rash, exfoliative dermatitis, urticaria, acne, rashes vezykulobulozni, eczema, alopecia, psoriasis, seborrhea, dry skin, itching, excessive sweating, skin ulcer, increased lacrimation, frequent flashing, external otitis, amblyopia, deafness, diplopia, eye hemorrhage, photophobia, dry eye, eye pain, ringing in ear, middle ear inflammation, cataracts, loss of taste, blepharitis, conjunctivitis, ear pain, pain abominator the breast, cervicitis, galactorrhoea, anorhazmiya, burning in the urogenital system, Glycosuria, gynecomastia (increased breast in men), urolithiasis, painful erections, cystitis, urinary accelerated, leykoreya, urinary retention, hematuria, dysuria, amenorrhea, premature ejaculation, vaginal bleeding, vaginal candidiasis, renal failure, uterinal bleeding menorahiya, albuminuria, kidney stones, nikturiya, abominator urgency to urinate, incontinence, pain throat, tightness in abominator back, heaviness in the abominator candidiasis, throat tightness, CM Mendelssohn, heat stroke, pain in the pelvic area, Polymerase Chain Reaction edema, photosensitivity, oral pain, chills, jaw stiffness, bloating, feeling of pressure abominator chest flu-like s-m, peripheral edema, pain in the chest, neck, hyperkalaemia, gout, gipernatriemiya, cyanosis, Hyper-reactive Malarial Splenomegaly of abominator hypoglycemic reaction, dehydration, edema, hypercholesterolemia, hyperglycemia, hypokalemia, diabetes, elevated ALT levels, hyperlipidemia, hypoglycemia, thirst, increased content of urea in the blood, hyponatremia, increased AST level, increased alkaline phosphatase, iron deficiency anemia, elevated creatinine, bilirubinemiya, increased LDH Obesity, weight loss, increased CPK.
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